{"id":1592,"date":"2025-10-16T10:46:27","date_gmt":"2025-10-16T13:46:27","guid":{"rendered":"https:\/\/inctnanoagro.com.br\/?p=1592"},"modified":"2025-12-11T10:07:24","modified_gmt":"2025-12-11T13:07:24","slug":"nanoparticulas-liberadoras-de-oxido-nitrico-plantas-mais-resistentes-a-seca","status":"publish","type":"post","link":"https:\/\/inctnanoagro.com.br\/en\/nanoparticulas-liberadoras-de-oxido-nitrico-plantas-mais-resistentes-a-seca\/","title":{"rendered":"Nitric Oxide-Releasing Nanoparticles: Making Plants More Drought-Resilient"},"content":{"rendered":"<p><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone wp-image-1594 size-large\" src=\"https:\/\/inctnanoagro.com.br\/wp-content\/uploads\/2025\/10\/Vitrine-Oxido-Nitrico-819x1024.webp\" alt=\"\" width=\"800\" height=\"1000\" srcset=\"https:\/\/inctnanoagro.com.br\/wp-content\/uploads\/2025\/10\/Vitrine-Oxido-Nitrico-819x1024.webp 819w, https:\/\/inctnanoagro.com.br\/wp-content\/uploads\/2025\/10\/Vitrine-Oxido-Nitrico-240x300.webp 240w, https:\/\/inctnanoagro.com.br\/wp-content\/uploads\/2025\/10\/Vitrine-Oxido-Nitrico-768x960.webp 768w, https:\/\/inctnanoagro.com.br\/wp-content\/uploads\/2025\/10\/Vitrine-Oxido-Nitrico-10x12.webp 10w, https:\/\/inctnanoagro.com.br\/wp-content\/uploads\/2025\/10\/Vitrine-Oxido-Nitrico.webp 1080w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">Solution<\/span><\/h3>\n<p><i><span style=\"font-weight: 400;\">Biodegradable nitric oxide (NO)-releasing nanoparticles that strengthen seeds and seedlings, enhancing their resistance to drought.<\/span><\/i><\/p>\n<h3><span style=\"font-weight: 400;\">What is the technological basis of this solution?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The technology is based on biodegradable polymeric nanoparticles that gradually release nitric oxide (NO). When applied to <\/span><b>seeds or seedlings<\/b><span style=\"font-weight: 400;\">, these nanoparticles improve vigor and germination, <\/span><b>reinforcing plant growth and tolerance to climatic stress<\/b><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Nitric oxide is a key signaling molecule in plants, involved in processes such as germination, root development, and responses to environmental stress. By encapsulating NO-donor molecules at the nanoscale, the gas no longer dissipates quickly into the environment and is instead released locally and over time. This sustained release promotes greater physiological efficiency \u2014 from the seed stage through field establishment.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The formulation was developed and validated by research teams at State University of Londrina (UEL), led by Prof. Halley Caixeta, in collaboration with Prof. Amedea Seabra\u2019s group at the Federal University of ABC (UFABC), both members of the INCT NanoAgro network.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">What is innovative about it?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The innovation lies in integrating nanotechnology and plant physiology. The nanoparticles act as micro-reservoirs that protect and deliver NO precisely where and when the plant needs it. This gradual release ensures that seed treatment continues to benefit the plant after germination \u2014 a result not achieved with conventional priming methods.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In field trials with soybean, seeds treated with NO-releasing nanoparticles showed higher emergence rates, more developed roots, and increased nodulation, indicating greater nitrogen-use efficiency and resilience under water-stress conditions.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">What problem does this technology address?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Drought is one of the main causes of agricultural losses in Brazil. A 2024 study showed that between 1973 and 2023, droughts accounted for 11.65% of soybean yield losses, equivalent to 280 million tons of unharvested grain.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">During the 2024\/25 season, a new drought in Rio Grande do Sul reduced soybean production by 3 million tons (AgRural). Losses related to drought in 2024 alone reached R$1.5 billion in the agricultural sector.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">In this scenario, technologies that increase plant tolerance to water stress are essential \u2014 and that is precisely where the NO-releasing nanoparticles developed by INCT NanoAgro come into play.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">Who could benefit from this solution?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The technology has two main application routes in agribusiness:<\/span><\/p>\n<ol>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Seed Priming:<\/b><span style=\"font-weight: 400;\"> For seed companies, cooperatives, and producers seeking improved initial vigor and drought resistance. It can be integrated into industrial seed treatment lines or commercial agricultural biotechnology formulations.<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><b>Bioinputs for Furrow Application: <\/b><span style=\"font-weight: 400;\">Suitable for crops such as soybean, corn, and wheat, where early seedling establishment is critical to field performance.<\/span><\/li>\n<\/ol>\n<p>&nbsp;<\/p>\n<p><span style=\"font-weight: 400;\">This innovation is of particular interest to seed companies and cooperatives aiming to enhance plant vigor under drought conditions, as well as to bioinput and ag-biotech industries developing sustainable crop management solutions. It can also attract R&amp;D laboratories and universities focused on green technologies and the controlled release of bioactive molecules.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">What is the market potential?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The potential application field is broad and expanding.<\/span><\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">The <\/span><b>global seed treatment market<\/b><span style=\"font-weight: 400;\"> is projected to grow from <\/span><b>US$15.11 billion (2024)<\/b><span style=\"font-weight: 400;\"> to <\/span><b>US$38.88 billion by 2032<\/b><span style=\"font-weight: 400;\">, at a 12.5% CAGR (Fortune Business Insights). <\/span>12,5%<span style=\"font-weight: 400;\"> (Fortune Business Insights).<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">In Brazil alone, <\/span>he soybean seed market<span style=\"font-weight: 400;\"> generates <\/span><b>R$33.6 billion<\/b><span style=\"font-weight: 400;\"> per harvest <\/span>(ABRASS)<span style=\"font-weight: 400;\"> \u2014 a direct opportunity for applying NO-releasing nanoparticles in <\/span><i><span style=\"font-weight: 400;\">seed priming<\/span><\/i><span style=\"font-weight: 400;\"> .<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Meanwhile, the <\/span>bioinput segment<span style=\"font-weight: 400;\"> has been expanding by over <\/span><b>20% annually<\/b><span style=\"font-weight: 400;\">, reaching <\/span><b>R$5 billion<\/b><span style=\"font-weight: 400;\"> in sales in the 2023\/24 season (CropLife Brasil), with more than <\/span><b>660 registered products<\/b><span style=\"font-weight: 400;\"> at the <\/span>Ministry of Agriculture (MAPA)<span style=\"font-weight: 400;\">\u2014 reflecting a favorable regulatory environment for biological and nanotechnological innovations.<\/span><\/li>\n<\/ul>\n<p><span style=\"font-weight: 400;\">These indicators position NO nanotechnology as a <\/span>a dual-market opportunity<span style=\"font-weight: 400;\">applicable to both <\/span><b>seed treatment<\/b><span style=\"font-weight: 400;\"> and <\/span><b>bioinputs for furrow application<\/b><span style=\"font-weight: 400;\">, two strategic innovation vectors for sustainable agriculture.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">What are the key differentiators of the technology?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The technology is versatile, suitable for both seed and furrow applications, and uses biodegradable, non-toxic materials. Built upon over a decade of research in plant physiology and nanotechnology, it has demonstrated proven gains in germination, vigor, and nodulation, leading to improved performance and drought resistance.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">The research is currently in the scaling-up phase, adapting the formulation to industrial processes and expanding its potential for large-scale field applications.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cThe idea is to ensure that NO reaches plant cells more effectively and is released gradually, securing the desired physiological benefits,\u201d explains Prof. <\/span>Halley Caixeta<span style=\"font-weight: 400;\">, project coordinator at UEL.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">What is its technology readiness level?<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">The technology is currently at <\/span><strong>TRL 6 \u2014 validated in relevant environments<\/strong><span style=\"font-weight: 400;\"><strong>,<\/strong> com testes realizados em campo experimental e comprova\u00e7\u00e3o dos efeitos fisiol\u00f3gicos e agron\u00f4micos em culturas comerciais como a soja, milho e trigo.<\/span><\/p>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">Research Team and Institutions<\/span><\/h3>\n<p>&nbsp;<\/p>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prof. Halley Caixeta Oliveira \u2013 State University of Londrina (UEL)<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prof. Amedea Barozzi Seabra \u2013 Federal University of ABC (UFABC)<\/span><\/li>\n<\/ul>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Prof. Claudemir Zucareli \u2013 UEL<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Diego Genu\u00e1rio\u00a0 Gomes \u2013 UEL<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Andr\u00e9 Sampaio Ferreira \u2013 UEL<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Beatriz Larissa de Souza \u2013 UEL<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Bruna C. R. Gomes &#8211; UEL<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Talita Silveira Amador &#8211; UEL<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Jo\u00e3o Pedro Chacon Pereira &#8211; UEL<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Joana C. Pieretti \u2013 UFABC<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Milena T. Pelegrino \u2013 UFABC<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><span style=\"font-weight: 400;\">Roberta Albino dos Reis \u2013 UFABC<\/span><\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<h3><span style=\"font-weight: 400;\">Market Data Sources<\/span><\/h3>\n<ul>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.agriculture.com\/agrural-cuts-brazil-s-2024-25-soy-crop-forecast-citing-drought-11702764\"><span style=\"font-weight: 400;\">AgRural Cuts Brazil\u2019s 2024\/25 Soy Crop Forecast Citing Drought<\/span><\/a><span style=\"font-weight: 400;\">\u00a0\u00a0\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.mdpi.com\/2077-0472\/14\/12\/2144\"><span style=\"font-weight: 400;\">Soybean Yield Losses Related to Drought Events in Brazil: Spatial\u2013Temporal Trends over Five Decades and Management Strategies<\/span><\/a><span style=\"font-weight: 400;\">\u00a0\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.agromarechal.com.br\/noticia.php?id=1564\"><span style=\"font-weight: 400;\">Seca arrasadora: Mais de R$ 360 milh\u00f5es em perdas na agricultura<\/span><\/a><span style=\"font-weight: 400;\">\u00a0<\/span><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/abrass.org.br\/noticias\/cadeia-de-sementes-de-soja-movimentou-r-33-6-bilhoes-na-safra-2022-23\"><span style=\"font-weight: 400;\">ABRASS \u2013 Cadeia de sementes de soja movimentou R$ 33,6 bilh\u00f5es na safra 2022\/23<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.marketsandmarkets.com\/Market-Reports\/seed-treatment-market-503.html\"><span style=\"font-weight: 400;\">MarketsandMarkets \u2013 Seed Treatment Market Report<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/www.fortunebusinessinsights.com\/pt\/industry-reports\/seed-treatment-market-100156\"><span style=\"font-weight: 400;\">Fortune Business Insights \u2013 Seed Treatment Market Report<\/span><span style=\"font-weight: 400;\"><br \/>\n<\/span><\/a><a href=\"https:\/\/www.gov.br\/agricultura\/pt-br\/assuntos\/noticias\/lider-global-na-utilizacao-de-bioinsumos-brasil-apresenta-panorama-regulatorio-de-registros-biologicos-na-abim\"><span style=\"font-weight: 400;\">MAPA \u2013 Panorama regulat\u00f3rio dos bioinsumos<\/span><\/a><\/li>\n<li style=\"font-weight: 400;\" aria-level=\"1\"><a href=\"https:\/\/croplifebrasil.org\/dados-e-estatisticas-correta\/\">CropLife Brasil \u2013 Dados e estat\u00edsticas do setor de biol\u00f3gicos<\/a><\/li>\n<\/ul>","protected":false},"excerpt":{"rendered":"<p>&nbsp; Solu\u00e7\u00e3o Nanopart\u00edculas liberadoras de \u00f3xido n\u00edtrico que fortalecem sementes e pl\u00e2ntulas e aumentam a sua resist\u00eancia \u00e0 seca. Qual \u00e9 a base tecnol\u00f3gica dessa solu\u00e7\u00e3o? A tecnologia utiliza nanopart\u00edculas polim\u00e9ricas biodegrad\u00e1veis, capazes de liberar \u00f3xido n\u00edtrico (NO) de forma gradual. Aplicadas em sementes ou mudas, as nanopart\u00edculas elevam o vigor e a germina\u00e7\u00e3o, fortalecendo [&hellip;]<\/p>","protected":false},"author":4,"featured_media":1597,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,43],"tags":[],"class_list":["post-1592","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias","category-vitrine-tecnologica"],"_links":{"self":[{"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/posts\/1592","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/comments?post=1592"}],"version-history":[{"count":10,"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/posts\/1592\/revisions"}],"predecessor-version":[{"id":1646,"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/posts\/1592\/revisions\/1646"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/media\/1597"}],"wp:attachment":[{"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/media?parent=1592"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/categories?post=1592"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/inctnanoagro.com.br\/en\/wp-json\/wp\/v2\/tags?post=1592"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}